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Colloid

Fri, 12/21/2007 - 12:17 — oxygen

Colloids

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-derived from either plasma proteins or synthetic polymers of glucose
Blood derived colloids contain:
-albumin 5%
-albumin 25%
-plasma protein fraction 5%
synthetic colloids contain

Dextrose starches
-dextran 40 (MW 40,000) increases blood in microcirculation via decreased viscosity
-dextran 70 (MW 70,000) greater volume expander than dextran 40
-may be antigenic
-mild and severe anaphylactic reactions are possible

-hetastarch 6% (MW  450,000)
-effective volume expander
-less expensive than albumin
-nonantigenic
-rare anaphylactic reactions
-less coagulation effects compared to other colloids

Indications for colloid resusitation:
-fluid resusitation in severely dehydrated patients (ex. hemorrhagic shock)
-fluid resusitation in patient with hypoalbuminemia
-conditions with loss of large amounts of proteins (ex. burns)

Comments

Mon, 04/12/2010 - 20:57 — examcert

I can handle it myself.Let's

I can handle it myself.Let's see you do it.Cisco 646-656 I'll be ready within five minutes.Cisco 642-504 Can I go now!CCDA 640-863 Stingy bastard! He didn't even pay for my dinner! What a stingy bastard.

Tue, 10/20/2009 - 23:44 — curt

Stabilization serves to

Stabilization serves to prevent colloids from aggregating. Steric stabilization and electrostatic stabilization are the two main mechanisms for colloid stabilization.When I was in college for EX0-103 exam .I often visit medical conferences.Electrostatic stabilization is based on the mutual repulsion of like electrical charges. In general, different phases have different charge affinities, so that a electrical double layer forms at any interface.One of my HP0-A01 exam teacher always guide us about different medical concepts.Small particle sizes lead to enormous surface areas, and this effect is greatly amplified in colloids. In a stable colloid, mass of a dispersed phase is so low that its buoyancy or kinetic energy is too weak to overcome the electrostatic repulsion between charged layers of the dispersing phase.I have a friend who is preparing for HP0-J22 exam and he often discuss with me about medical sciences.The charge on the dispersed particles can be observed by applying an electric field: All particles migrate to the same electrode and therefore must all have the same sign charge.