John's Clinical Insight
Some of you might take what I’m about to write as “insulting”. Still there are others that will know exactly where I’m coming from...read more
User login
Colloid
Colloids
-derived from either plasma proteins or synthetic polymers of glucose
Blood derived colloids contain:
-albumin 5%
-albumin 25%
-plasma protein fraction 5%
synthetic colloids contain
Dextrose starches
-dextran 40 (MW 40,000) increases blood in microcirculation via decreased viscosity
-dextran 70 (MW 70,000) greater volume expander than dextran 40
-may be antigenic
-mild and severe anaphylactic reactions are possible
-hetastarch 6% (MW 450,000)
-effective volume expander
-less expensive than albumin
-nonantigenic
-rare anaphylactic reactions
-less coagulation effects compared to other colloids
Indications for colloid resusitation:
-fluid resusitation in severely dehydrated patients (ex. hemorrhagic shock)
-fluid resusitation in patient with hypoalbuminemia
-conditions with loss of large amounts of proteins (ex. burns)
Search
"When you treat a disease, first treat the mind."
May Winners
Top 5 users
| User | Points |
|---|---|
| nomzz | 21 |
| Alia | 20 |
| cdmc1st2006 | 13 |
| bluefinga | 12 |
| moosa | 11 |
| More details | |
Comments
Stabilization serves to
Stabilization serves to prevent colloids from aggregating. Steric stabilization and electrostatic stabilization are the two main mechanisms for colloid stabilization.When I was in college for EX0-103 exam .I often visit medical conferences.Electrostatic stabilization is based on the mutual repulsion of like electrical charges. In general, different phases have different charge affinities, so that a electrical double layer forms at any interface.One of my HP0-A01 exam teacher always guide us about different medical concepts.Small particle sizes lead to enormous surface areas, and this effect is greatly amplified in colloids. In a stable colloid, mass of a dispersed phase is so low that its buoyancy or kinetic energy is too weak to overcome the electrostatic repulsion between charged layers of the dispersing phase.I have a friend who is preparing for HP0-J22 exam and he often discuss with me about medical sciences.The charge on the dispersed particles can be observed by applying an electric field: All particles migrate to the same electrode and therefore must all have the same sign charge.