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Extracellular Fluids

Fri, 12/21/2007 - 12:07 — oxygen

EXTRACELLULAR FLUID

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-composed of intravascular compartment and interstitial compartment
-Na+ is the most important determinant for the extracellular osmotic pressure and volume
-changes in total body sodium content generally reflects the extracellular volume
Extracellular fluid provides a medium for:
-cellular nutrients and electrolyes
-cellular waste products

Interstitial fluid
Generally associated with:
-extracellular proteoglycans which forms a gel
-negative pressure  -5mmHg
-edema is generally associated with a positive interstitial fluid pressure

Intravascular fluid
-small electrolytes are able to pass freely from interstitium into the intravascular space
-identical electrolyte composition between the plasma intravascular space and interstitium
-plasma proteins (albumin) are the only osmotically active solute in the plasma that is not exchanged w.in the interstitial fluid
clinical example: tissue edema
-occurs with increased extracellular fluid volume
-interstitial pressure becomes positive
-additional increases in extracellular fluid expands the interstitial compartment
-resultant tissue edema

Comments

Thu, 03/04/2010 - 04:37 — pass4sure

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Wed, 09/30/2009 - 23:50 — gul khan

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Tue, 09/15/2009 - 02:25 — nomzz

Someone may get information

Someone may get information from this , but should analyze that whether it is true or not...Extracellular fluid (ECF) usually denotes all body fluid outside of cells. The remainder is called intracellular fluid.
In some animals, including mammals, the extracellular fluid can be divided into two major subcompartments, interstitial fluid and blood plasma. The extracellular fluid also includes the transcellular fluid; making up only about 2.5 percent of the ECF.actually i was surfing net to get data related to my projects of 640-822 , 640-863 , 642-061 and in the meantime came here...And find this post different one!
In humans, the normal glucose concentration of extracellular fluid that is regulated by homeostasis is approximately 5 mM.
The pH of extracellular fluid is tightly regulated by buffers around 7.4.
The volume of ECF is typically 15L (of which 12L is interstitial fluid and 3L as plasma)